4.2 Posology and method of administration For intravenous infusion, intravenous injection or intramuscular injection. NOTE: All doses are given in terms of ketamine base Adults, elderly (over 65 years) and children: For surgery in elderly patients ketamine has been shown to be suitable either alone or supplemented with other anaesthetic agents. Preoperative preparations Ketamine has been safely used alone when the stomach was not empty. However, since the need for supplemental agents and muscle relaxants cannot be predicted, when preparing for elective surgery it is advisable that nothing be given by mouth for at least six hours prior to anaesthesia. Premedication with an anticholinergic agent (e.g. atropine, hyoscine or glycopyrolate) or another drying agent should be given at an appropriate interval prior to induction to reduce ketamine- induced hypersalivation. Midazolam, diazepam, lorazepam, or flunitrazepam used as a premedicant or as an adjunct to ketamine, have been effective in reducing the incidence of emergence reactions. Onset and duration As with other general anaesthetic agents, the individual response to Ketamine is somewhat varied depending on the dose, route of administration, age of patient, and concomitant use of other agents, so that dosage recommendation cannot be absolutely fixed. The dose should be titrated against the patient's requirements. Because of rapid induction following intravenous injection, the patient should be in a supported position during administration. An intravenous dose of 2 mg/kg of bodyweight usually produces surgical anaesthesia within 30 seconds after injection and the anaesthetic effect usually lasts 5 to10 minutes. An intramuscular dose of 10 mg/kg of bodyweight usually produces surgical anaesthesia within 3 to 4 minutes following injection and the anaesthetic effect usually lasts 12 to 25 minutes. Return to consciousness is gradual. A. Ketamine as the sole anaesthetic agent Intravenous Infusion The use of Ketamine by continuous infusion enables the dose to be titrated more closely, thereby reducing the amount of drug administered compared with intermittent administration. This results in a shorter recovery time and better stability of vital signs. A solution containing 1 mg/ml of ketamine in dextrose 5% or sodium chloride 0.9% is suitable for administration by infusion. General Anaesthesia Induction An infusion corresponding to 0.5 – 2 mg/kg as total induction dose. Maintenance of anaesthesia Anaesthesia may be maintained using a microdrip infusion of 10 - 45 microgram/kg/min (approximately 1 – 3 mg/min). The rate of infusion will depend on the patient's reaction and response to anaesthesia. The dosage required may be reduced when a long acting neuromuscular blocking agent is used. Intermittent Injection Induction Intravenous Route
Ketalar (Ketamine HCL) 100mg/ml injection
Ketalar (Ketamine HCL) 100mg/ml vials/injections:
Ketalar (Ketamine HCL) used before surgery or a medical or dental procedure to produce loss of consciousness. May be used on its own or with another medicine. This medicine is a type of anesthetic.
You can buy Ketalar (Ketamine HCL) 100mg/ml injections online without prescription (No RX) .
RESEARCH CHEMICALS & POWDERS